Galectin-3: clinical utility and prognostic value in patients with heart failure
نویسندگان
چکیده
منابع مشابه
Prognostic Value of Galectin-3 in Patients with Heart Failure
Galectins are a family of soluble β-galactoside-binding lectins that have important role in inflammation, immunity, and cancer. Galectin-3 as a part of this lectin family plays a very important role in development of heart failure. According to recent papers, galectin-3 plasma level correlates with heart failure outcome, primarily with rehospitalisation and death from heart failure. This paper ...
متن کاملPrognostic Value of Serial Galectin‐3 Measurements in Patients With Acute Heart Failure
BACKGROUND Several clinical studies have evaluated the association between galectin-3 levels and outcome in patients with heart failure (HF). However, little is known about the predictive value of repeated galectin-3 measurements. This study evaluates the prognostic value of repeated time-dependent galectin-3 measurements in acute HF patients. METHODS AND RESULTS In the TRIUMPH (Translational...
متن کاملPrognostic value of changes in galectin-3 levels over time in patients with heart failure: data from CORONA and COACH.
BACKGROUND In several cross-sectional analyses, circulating baseline levels of galectin-3, a protein involved in myocardial fibrosis and remodeling, have been associated with increased risk for morbidity and mortality in patients with heart failure (HF). The importance and clinical use of repeated measurements of galectin-3 have not yet been reported. METHODS AND RESULTS Plasma galectin-3 was...
متن کاملPrognostic Value of the Interaction between Galectin-3 and Antigen Carbohydrate 125 in Acute Heart Failure
AIMS Galectin-3 (Gal-3) and carbohydrate antigen 125 (CA125) have emerged as robust prognostic biomarkers in heart failure. Experimental data have also suggested a potential molecular interaction between CA125 and Gal-3; however, the biological and clinical relevance of this interaction is still uncertain. We sought to evaluate, in patients admitted for acute heart failure, the association betw...
متن کاملThe prognostic value of sST2 and galectin-3 considering different aetiologies in non-ischaemic heart failure
Objective Several studies indicate a prognostic value of sST2 and galectin-3 in heart failure (HF). While previous studies focused on ischaemic cause of HF, we investigated the role of sST2 and galectin-3 in patients with non-ischaemic dilated cardiomyopathy (DCM). Methods sST2 and galectin-3 serum concentrations were measured in 262 subjects with DCM. Survival rates were determined for all-c...
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ژورنال
عنوان ژورنال: Research Reports in Clinical Cardiology
سال: 2013
ISSN: 1179-8475
DOI: 10.2147/rrcc.s28562